2024 NFL Week 4: Betting odds and lines for every game

The New York Giants and the Dallas Cowboys kick off the NFL’s Week 4 slate of games with a Thursday night matchup at the Meadowlands. The 1-2 Cowboys enter the game as favorites over the 1-2 Giants, who are fresh off their first win of the season. This is the final full week of action before teams start going on bye in Week 5, which means 13 games on Sunday along with another Monday Night Football doubleheader, this time featuring the Tennessee Titans and Miami Dolphins (7:30 p.m. ET on ESPN) and the Seattle Seahawks and Detroit Lions (8:15 p.m. ET on ABC and ESPN+).

Here’s a look at all the Week 4 games. Football Power Index (FPI) by ESPN Sports Analytics. Odds current as of publication time. For most current odds go to ESPN BET

MORE NFL BETTING CONTENT: My First Bet: Early picks for NFL Week 4

Dallas Cowboys -5.5 vs. New York Giants
Thursday, 8:15 p.m. ET, Prime Video

Money Line: Cowboys (-230) ; Giants (+195)
Total: 45.5; Opened: 44.5
FPI favorite: Cowboys by 3.1, 57.1% to win outright

Cincinnati Bengals -4.5 vs. Carolina Panthers
Sunday, 1 p.m. ET, FOX

Money Line: Bengals (-210) ; Panthers (+175)
Total: 48.5; Opened: 44.5
FPI favorite: Bengals by 6, 65.1% to win outright

Philadelphia Eagles -2.5 vs. Tampa Bay Buccaneers
Sunday, 1 p.m. ET, FOX

Money Line: Eagles (-130) ; Buccaneers (+110)
Total: 44.5; Opened: 46.5
FPI favorite: Eagles by 4.2, 61.3% to win outright

Denver Broncos vs. New York Jets -7.5
Sunday, 1 p.m. ET, CBS

Money Line: Broncos (+290) ; Jets (-360)
Total: 38.5; Opened: 38.5
FPI favorite: Jets by 8.4, 70% to win outright

Minnesota Vikings vs. Green Bay Packers -2.5
Sunday, 1 p.m. ET, CBS

Money Line: Vikings (+120) ; Packers (-140)
Total: 43.5; Opened: 42.5
FPI favorite: Packers by 2.4, 55.7% to win outright

Los Angeles Rams vs. Chicago Bears -2.5
Sunday, 1 p.m. ET, FOX

Money Line: Rams (+125) ; Bears (-145)
Total: 40.5; Opened: 40.5
FPI favorite: Rams by 0.3, 49.9% to win outright

New Orleans Saints vs. Atlanta Falcons -1.5
Sunday, 1 p.m. ET, FOX

Money Line: Saints (+105) ; Falcons (-125)
Total: 42.5; Opened: 43.5
FPI favorite: Saints by 0.4, 51.3% to win outright

Pittsburgh Steelers -1.5 vs. Indianapolis Colts
Sunday, 1 p.m. ET, CBS

Money Line: Steelers (-125) ; Colts (+105)
Total: 39.5; Opened: 39.5
FPI favorite: Steelers by 1.8, 54% to win outright

Jacksonville Jaguars vs. Houston Texans -7
Sunday, 1 p.m. ET, CBS

Line movement: Opened Texans -4.5

Money Line: Jaguars (+250) ; Texans (-300)
Total: 45.5; Opened: 45.5
FPI favorite: Texans by 4.3, 61.1% to win outright

New England Patriots vs. San Francisco 49ers -9.5
Sunday, 4:05 p.m. ET, FOX

Money Line: Patriots (+400) ; 49ers (-525)
Total: 39.5; Opened: 40.5
FPI favorite: 49ers by 11.8, 77.3% to win outright

Washington Commanders vs. Arizona Cardinals -3
Sunday, 4:05 p.m. ET, FOX

Line movement: Opened Cardinals -5.5

Money Line: Commanders (+145) ; Cardinals (-170)
Total: 50.5; Opened: 49.5
FPI favorite: Cardinals by 4.2, 61.5% to win outright

Cleveland Browns vs. Las Vegas Raiders -1
Sunday, 4:25 p.m. ET, CBS

Money Line: Browns (-105) ; Raiders (-115)
Total: 37.5; Opened: 37.5
FPI favorite: Browns by 0.3, 51.2% to win outright

Kansas City Chiefs -8.5 vs. Los Angeles Chargers
Sunday, 4:25 p.m. ET, CBS

Money Line: Chiefs (-425) ; Chargers (+340)
Total: 39.5; Opened: 39.5
FPI favorite: Chiefs by 5.1, 63.3% to win outright

Buffalo Bills vs. Baltimore Ravens -2.5
Sunday, 8:20 p.m. ET, NBC, Peacock

Money Line: Bills (+115) ; Ravens (-135)
Total: 46.5; Opened: 45.5
FPI favorite: Bills by 2.3, 56.9% to win outright

Tennessee Titans vs. Miami Dolphins -1
Monday, 7:30 p.m. ET, ESPN

Money Line: Titans (-110) ; Dolphins (-110)
Total: 36.5; Opened: 36.5
FPI favorite: Titans by 2.3, 56.6% to win outright

Seattle Seahawks vs. Detroit Lions -4
Monday, 8:15 p.m. ET, ABC, ESPN+

Money Line: Seahawks (+165) ; Lions (-195)
Total: 47.5; Opened: 48.5
FPI favorite: Lions by 4.6, 62.1% to win outright